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Bio-Techne corporation
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The CD20 Antibody (IGEL/1497R) [Alexa Fluor® 350] from Novus is a CD20 antibody to CD20. This antibody reacts with Human. The CD20 antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.
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The CD20 Antibody (IGEL/1497R) [Alexa Fluor® 647] from Novus is a CD20 antibody to CD20. This antibody reacts with Human. The CD20 antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.
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Image Search Results
Journal: medRxiv
Article Title: Spatial mapping of Ethiopian cutaneous leishmaniasis lesions reveals distinct tissue level immune programs
doi: 10.64898/2026.02.04.26345554
Figure Lengend Snippet: A , Heatmap of top 100 DEGs in P1_L vs other lesional skin (P2-P5 L) (padj < 0.05, log2FC > ±0.25; Wilcoxon) B , UMAP of cytotoxicity signature in lesional skin (P1-P5). Top: composite score; right/below: four cytotoxic effector genes. C , Cytotoxicity score across all patients (Wilcoxon; P1_L vs P2-P5 L). D , Spatial map of cytotoxicity score in P1_L (middle), underlying H&E histology (left panel) and zoomed view of a representative area showing individual gene expression for selected genes (right). E, Cell type deconvolution (pie charts) of representative area (from D ). F , Fold enrichment of topics in high (≥Q3, top 25%) vs low ( Article Snippet: For separate experiment, sections were stained with Techniques: Gene Expression, Multiplex Assay, Immunofluorescence
Journal: Nature Communications
Article Title: Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma
doi: 10.1038/s41467-024-46220-z
Figure Lengend Snippet: A Schematic of GeoMx® DSP WTA workflow (created with BioRender.com). B , C Immunofluorescence staining of DLBCL tissues ( n = 87) and RLTs ( n = 24). In Group 1, CD68 stained macrophages (yellow), CD3 stained T cells (cyan), CD20 stained B cells (magenta), and SYTO 13 stained nuclei (blue). In Group 2, CD68 stained macrophages (yellow), NGFR illuminated LZ (green) and SYTO 13 stains nuclei (blue). After ROI selection, each cell type was segmented based on the staining signal and their corresponding masks were generated. Representative images are shown. Scale bar: 100 μm. Source data are provided as a file. D , E Cumulative density functions showed that the signatures of macrophages ( CD68 , CD163 , FCGR1A , and CSF1R ), T cells ( CD3D , CD3E , UBASH3A , CD2 , and TRBC2 ), and B cells ( MS4A1 , CD79A , CD79B , CD19 , and PAX5 ) were highly enriched in CD68+ regions, CD3+ regions, and CD20+ regions, respectively in RLTs and DLBCL tissues (Kolmogorov-Smirnov P < 0.05). Digital spatial profiling, DSP; whole transcriptome analysis, WTA; diffuse large B-cell lymphoma, DLBCL; reactive lymphoid tissues, RLTs; regions of interest, ROIs; areas of interest, AOIs; formalin-fixed paraffin-embedded, FFPE; light zone, LZ; dark zone, DZ; nerve growth factor receptor, NGFR.
Article Snippet: For Group 1, slides of DLBCL TMA were stained with macrophage marker CD68 (sc-20060 AF594, Santa Cruz biotechnology, Texas, USA), T-cell marker CD3 (A0452, Dako, California, USA),
Techniques: Immunofluorescence, Staining, Selection, Generated, Formalin-fixed Paraffin-Embedded